Important Safety Information

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Important Safety Information

Full Prescibing Information

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Indication and important safety information

INDICATION:

Strontium89 (strontium chloride Sr-89 Injection, USP) is used for the relief of bone pain in patients with bone metastases. You should only use Strontium89 if you have been diagnosed with metastatic bone cancer.

Important Safety Information:

  • Strontium89 may affect bone marrow and may cause white blood cell and platelet counts to be lower than normal. To monitor these effects, your doctor will perform regular blood tests before and after your injection, usually at least every other week until your levels have recovered. This may take up to 6 months. Your doctor will decide if it is safe for you to get a repeat injection, 90 days later, if needed. If you already have seriously decreased bone marrow function, your doctor may decide that you should not receive Strontium89.
  • Tell your doctor if you are pregnant or planning to become pregnant. Strontium89 may cause
    harm to your unborn baby and should not be used if you are pregnant or planning to become
    pregnant. You should not nurse your baby while using Strontium89.
  • You should not use Strontium89 if you do not have cancer in your bone.
  • You should not use Strontium89 if you are younger than 18 years old.
  • You may feel flushed (your skin may get red and warm) right after your injection.
  • Side effects in clinical studies:
    • One patient died from a blood infection caused by a severely low white blood cell count.
    • A small number of patients reported a mild and brief increase in bone pain within 36 to 72 hours after injection that was controlled with oral pain medication.
    • One patient had chills and fever 12 hours after injection but recovered.

These are not all of the side effects of Strontium89. If you have any questions or concerns about side effects, you should contact your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information.

TAKING STRONTIUM89

How is Strontium89 given?

Strontium89 is an IV injection given by your doctor. If needed, retreatment is possible after 90 days.

Over 1 to 2 Minutes

Injected over 1 to 2 minutes

What to expect when taking Strontium89

A single injection may get you on the road to lasting pain relief. If you and your cancer care team decide that Strontium89 is right for you or your loved one, here’s what you need to know before, during, and after the injection.

Before treatment

Before receiving Strontium89, you will get a blood test to make sure your blood cell counts are within an acceptable range and it’s okay for you to receive your injection.

During treatment

You will get an IV into your vein over the course of 1 to 2 minutes.

After treatment

There are no restrictions regarding being in the presence of other people after receiving Strontium89. You will need to receive a blood test once every other week after injection to monitor your white blood cell and platelet counts. Don’t worry if you don’t feel pain relief right away; many patients report relief within 7 to 20 days.

Take special care for 2 weeks

Because Strontium89 is eliminated via bodily fluids such as urine and feces, follow good hygiene practices to avoid radiation exposure immediately after injection and for 2 weeks thereafter.

For 2 weeks after injection, it’s important to:

Wash hands thoroughly every time you use or clean the bathroom.

Men and women should sit on the toilet and flush 2 times after each use.

Wear gloves and gowns if cleaning up bodily waste.

If sheets and clothing become soiled with bodily fluids, wash them right away and separately from other clothes.

Wash away any blood if you cut or injure yourself and apply a bandage.

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Indication and important safety information

INDICATION:

Strontium89 (strontium chloride Sr-89 Injection, USP) is used for the relief of bone pain in patients with bone metastases. You should only use Strontium89 if you have been diagnosed with metastatic bone cancer.

Important Safety Information:

  • Strontium89 may affect bone marrow and may cause white blood cell and platelet counts to be lower than normal. To monitor these effects, your doctor will perform regular blood tests before and after your injection, usually at least every other week until your levels have recovered. This may take up to 6 months. Your doctor will decide if it is safe for you to get a repeat injection, 90 days later, if needed. If you already have seriously decreased bone marrow function, your doctor may decide that you should not receive Strontium89.
  • Tell your doctor if you are pregnant or planning to become pregnant. Strontium89 may cause harm to your unborn baby and should not be used if you are pregnant or planning to become pregnant. You should not nurse your baby while using Strontium89.
  • You should not use Strontium89 if you do not have cancer in your bone.
  • You should not use Strontium89 if you are younger than 18 years old.
  • You may feel flushed (your skin may get red and warm) right after your injection.
  • Side effects in clinical studies:
    • One patient died from a blood infection caused by a severely low white blood cell count.
    • A small number of patients reported a mild and brief increase in bone pain within 36 to 72 hours after injection that was controlled with oral pain medication.
    • One patient had chills and fever 12 hours after injection but recovered.

These are not all of the side effects of Strontium89. If you have any questions or concerns about side effects, you should contact your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information.